John Marshall is a Professor of Surgery at the University of Toronto, and a trauma surgeon and intensivist at St. Michael’s Hospital in Toronto, Canada. His academic interests are sepsis, trauma, and the innate immune response. His laboratory studies the cellular mechanisms that prolong neutrophil survival in critical illness by preventing neutrophil programmed cell death, or apoptosis. Professor Marshall has an active clinical research interest in sepsis and ICU-acquired infection, and in the design of clinical trials and outcome measures. He has published more than 260 manuscripts, and 70 book chapters, and is the editor of 2 books. He is the founding chair of the International Forum of Acute Care Trialists (InFACT) – a global network of investigator-led critical care clinical research groups, and a member of the Council of the World Federation of Societies of Intensive and Critical Care Medicine and of the executive committee of the International Severe Acute Respiratory Infections Consortium. He is past-chair of the International Sepsis Forum, past-President of the Surgical Infection Society, and past-chair of the Canadian Critical Care Trials Group. He has given invited lectures at more than 400 meetings around the world, and is a member of the editorial boards of seven journals.